Shifted from Wnt to Hedgehog Signaling Pathways
AbstractTwo papers in recent issue of Developmental Cell (Glise et al. 2005 and Gorfinkiel et al. 2005) have shown that Shifted, a Drosophila ortholog of Wnt Inhibitory Factor (WIF), modulates the distribution of Hedgehog protein in the wing imaginal disc through a Wnt-independent mechanism.
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