e martë, mars 15, 2005

Ras and Rap: Are Former Enemies Now Friends?

The small GTPase Rap1 was originally thought to function as an antagonist of Ras. A recent paper by Mishra et al. (2005) provides evidence that Ras and Rap1 function in parallel to activate Raf downstream of the Torso receptor tyrosine kinase in Drosophila.