e martë, shkurt 22, 2005

Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly

A targeted increase in mitochondrial uncoupling in adult neurons reduced the generation of reactive oxygen species (ROS) and extended life span without diminishing critical physiological systems in the fly. This defines a new point for life span intervention, modifying the metabolic efficiency of the mitochondria. The successful initiation of this intervention during adult life in the fly suggests that selective alterations in mitochondrial physiology could make a positive difference in health and longevity for adults of other species.

posted by Selfmaderadio @ 4:36 e pasdites